Archaeal, bacterial and eukaryotic tubulins. (A) Phylogenetic tree of the FtsZ-tubulin superfamily. The tree is rooted by FtsZ proteins; TreeFinder/Molphy bootstrap values are indicated for major branches. The sequences are denoted as in Figure 1. Asterisks mark diverged ciliate tubulins . (B) Genome neighborhood of bacterial and thaumarchaeal tubulins. Genes are marked as follows: A, bacterial tubulin A; B, bacterial tubulin B; C, tetratricopeptide repeat protein referred to as bacterial kinesin light chain in ref (PMIDS 12486237 and 17942428); T, thaumarchaeal tubulin; S, Snf7; 1, putative serine/threonine kinase; 2, pyruvate phosphate dikinase; 3, aspartate aminotransferase; 4, response regulator with a HTH DNA-binding domain; 5, glucose/sorbose dehydrogenase; 6, cysteine synthase; 7, DEAD/DEAH box helicase; 8, Major facilitator superfamily MFS 1; 9, TATA-box binding protein; 10, zinc-binding CMP/dCMP deaminase; 11, DNA polymerase I; 12, conserved hypothetical protein; 13, triosephosphate isomerase; and 14, AsnC family transcriptional regulator. Syntenic regions between Nitrosarachaeum koreensis and Nitrosopumilis maritimus are shaded.
Yutin and Koonin Biology Direct 2012 7:10 doi:10.1186/1745-6150-7-10