Biology Direct serves the life science research community as an open access, peer-reviewed online journal, providing authors and readers with an alternative to the traditional model of peer review. Biology Direct considers original research articles, hypotheses, comments, discovery notes and reviews in subject areas currently identified as those most conducive to the open review approach, primarily those with a significant non-experimental component.
- Eugene Koonin, NCBI, NLM, NIH
- Laura Landweber, Princeton University
- David Lipman, NCBI, NLM, NIH
ReviewAn internally consistent parallel universe of knowledge, “Black Six Biology”, has emerged as a result of a pleiotropic mutation in the popular inbred mouse strain C57BL/6J.
ResearchTranslational selection does exist in human, but acts differentially on human genes, which is more pronounced in housekeeping genes that are expressed ubiquitously and consistently in most or all tissues.
HypothesisSilent mutations associated with autism cause a significant shift from optimal to suboptimal codons.
ResearchLong intergenic non-coding RNA with different stability might be involved in various cellular processes.
HypothesisThe diversity of parasites that control host behavior suggests that this phenomenon could be underestimated in humans: it is hypothesized that microorganisms could contribute to the spreading of some rituals.
ResearchA biologically meaningful and user-friendly method for identifying candidate hubs in gene co-expression networks.
ResearchVerified biochemical and bioinformatic predictions confirm that the two aminoacyl-tRNA synthetase classes (I and II) that now translate the genetic code arose on opposite strands of the same ancestral gene.
ReviewBringing up to date the orphan enzyme problem, more than 30% of activities are still lacking sequence information in databases.
Research"Yeast metabolic modeling connects function to human single nucleotide non-synonymous variation."
Unique model of peer review
Biology Direct offers a novel system of peer review, allowing authors to select suitable reviewers from the journal's Editorial Board; making the peer-review process open rather than anonymous; and making the reviewers' reports public, thus increasing the responsibility of the referees and eliminating sources of abuse in the refereeing process.
Biology Direct publishes in the following sections:
- Evolutionary Biology
- Mathematical Biology
- Non-coding DNA & RNA
- Structural & Molecular biology
- Systems Biology
For details of Section Editors and Editorial Board members, please see the Editorial Board page.
Edited by Dr Maureen O'Malley and Dr Yan Boucher
Published: 30 June 2011
Edited by Prof Marek Kimmel
Published: 20 April 2010
Edited by Dr Eugene Koonin
Published: 24 April 2009
Edited by Dr Eugene Koonin
Published: 9 July 2008
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